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Research Finds That Cholesterol And Autism Might Be Linked:- As per a new study, the researchers identified an autism arising from a cluster of genes that can regulate cholesterol metabolism in the body. The study was conducted by a team of researchers from Harvard Medical School, Massachusetts Institute of Technology and Northwestern University. The study got published in the journal Nature Medicine. They identified the shared molecular roots that are between lipid dysfunction and autism. They analyzed the DNA samples of the brain and came to a conclusion on this. The analysis showed that both the children and parents with autism showed alterations in the lipid blood.
The research also brought several new questions and some of the important ones among them are about how do lipid alterations drive neurodevelopmental dysfunction and how they could normalize lipid metabolism impact the outcomes of the disease. Senior investigator Isaac Kohane, chair of the Department of Biomedical Informatics in the Blavatnik Institute at Harvard Medical School said that their results are striking illustration of the complexity of autism. The research team started analyzing the patterns of the expressions of the genes from the brain samples that are contained in two large national brain banks. The autism is four times more common in males than females.
Around 6.5 percent of those with autism diagnosis had abnormal lipid levels. A molecular explanation to the establishment presents the genes are involved in cholesterol metabolism.